Health and Comfort
Some particles in the air can be removed by filtration.
However, mold can grow wherever there is enough moisture and dust mite allergens are too heavy to stay suspended long enough to get caught in a filter.
The above chart shows that to prevent mold growth it is good to maintain humidity below 50% relativity humidity, and dust mites are dormant and do not reproduce when the relative humidity is controlled below 45%.
Integrity Air offers whole house dehumidifiers/purifiers.
Not only do they use considerably less electricity than portable ones, they are also much quieter and have no tub of water that needs to be emptied.
Courtesy of "Jay Hoover, President, Integrity Air"